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The Impact of Particle Agglomeration on Flow Properties: An Imaging Ap…

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작성자 Isidro 댓글 0건 조회 4회 작성일 26-01-01 02:00

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Particle clustering profoundly affects the flow behavior of powders and granular materials across industries such as drug formulation, food manufacturing, ceramic production, and 3D printing. When individual particles form aggregates due to interparticle forces like intermolecular adhesion, Coulombic effects, or capillary condensation, the resulting agglomerates alter the material’s packing density, compressive behavior, and resistance to shear. These changes directly affect how the material moves through hoppers, mixers, conveyors, and reactors, often leading to inconsistent dosing, segregation, or even complete flow blockage.


Conventional flow analysis techniques like repose angle or Carr index offer bulk-level data but cannot uncover the nano- to micro-scale causes. This is where advanced imaging techniques offer a transformative advantage.


State-of-the-art tools like electron-enhanced optical imaging, 3D laser scanning, synchrotron microtomography, and image correlation allow researchers to observe clump formation in real time during actual industrial operations. These tools quantify cluster dimensions, geometry, packing patterns, and network formation, enabling a unambiguous connection between nano-scale structure and system-level response. For instance, high-resolution tomography visualizes 3D cluster topology in dynamic systems, pinpointing voids and flow barriers. Similarly, high-speed video combined with image analysis software can track the motion of individual agglomerates during shear, quantifying their deformation and breakage under stress.


Combining real-time imaging with rheological measurements facilitates the development of predictive, structure-driven flow models.


A recent experiment confirmed that agglomerates surpassing 200 µm in diameter cause a 40% drop in flow efficiency within pharmaceutical feeders. Such findings, derived from imaging, shape equipment parameters like hopper angle, agitation rate, or anti-clumping additives. It facilitates calibration of surface-modification techniques or drying cycles to mitigate capillary-driven bonding.


Additionally, imaging supports accurate transition from lab to production scale. Results from benchtop systems often misrepresent large-volume agglomeration trends due to scale-dependent forces. With spatially resolved imaging, engineers can spot incipient agglomeration zones that evade conventional sampling, allowing for 粒子形状測定 early corrections before commercial launch. This reduces costly downtime and improves product quality consistency.


Artificial intelligence applied to imaging data unlocks deeper patterns. Deep learning systems categorize agglomerate structures, measure abundance, and anticipate flow metrics from large-scale visual data. This strategy replaces expert judgment with algorithmic consistency applicable in any manufacturing site.


Ultimately, agglomeration is not a trivial side effect—it is a dominant factor in material handling. Advanced imaging offers the dual capability of visualization and measurement to master this behavior. Linking particle-level architecture to bulk performance allows industries to build optimized, robust, and future-ready processing lines.

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