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At single oral doses of 100 mg and 200 mg, transient dose-related impairment of color discrimination was detected using the Farnsworth- Munsell 100-hue test, with peak effects near the time of peak plasma levels. This finding is consistent with the inhibition of PDE6, which is involved in phototransduction in the retina. Subjects in the study reported this finding as difficulties in discriminating blue/green. An evaluation of visual function at doses up to twice the maximum recommended dose revealed no effects of VIAGRA on visual acuity, intraocular pressure, or pupillometry. Therefore, the use of such combinations is not recommended. Caution is advised when PDE5 inhibitors areco-administered with alpha-blockers.

What Drugs, Substances, or Supplements Interact with Viagra?

You may wonder how often certain side effects occur with this drug. Here’s some detail on several of the side effects this drug may cause. The following lists contain some of the key side effects that may occur while taking Viagra.
The medication can help you get an erection up to 4 hours after you’ve taken a dose. For more information about taking Viagra with other medications, see the "Viagra interactions" section below. And for more information about taking Viagra if you have heart or blood pressure problems, see the "Viagra precautions" section below.

Effectiveness and safety

You should take VIAGRA about one hour before you plan to have sex. The amount of time VIAGRA takes to work varies from person to person, but it normally takes between half an hour and one hour. Keep this medicine out of the sight and reach of children.

How to take sildenafil

Learn how to take Viagra safely to treat erectile dysfunction. However, the choice between Viagra and Cialis should not merely be based оn their duration and onset of асtion. Factors such as how frequentlу sexual activity is anticipated, individual response to the drugs, potential side effects, and the cost can all influence the best choice of treatment. Viagra is not the only medication available for treating erectile dysfunction. Other drugs in the market such as Ciаlis (tadalafil) аnd Levitra (vardenafil) serve a similar role.
If Viagra does not work for you, contact us via your account so that we can discuss your treatment options. However not everyone will experience these, and if they do side effects tend to be mild and last a short time. If Viagra doesn’t help you to get an erection or BUY XANAX WITHOUT PRESCRITION your erection doesn’t last long enough to complete sexual intercourse please talk to your GP. Sildenafil is a medicine used to treat erection problems (erectile dysfunction). The FDA's approval of sildenafil in 1998[26] was a ground-breaking commercial event for the treatment of ED, with sales exceeding US$1 billion. Subsequently, the FDA approved both vardenafil[27] and tadalafil in 2003.
NO then activates the enzyme guanylate cyclase, which results in increased levels of cyclic guanosine monophosphate (cGMP), producing smooth muscle relaxation in the corpus cavernosum and allowing inflow of blood. Penile erection is caused by the engorgement of the penis with blood. This engorgement occurs when the blood vessels delivering blood to the penis increase the delivery of blood and the blood vessels carrying blood away from the penis decrease the removal of blood. Under normal conditions, sexual stimulation leads to the production and release of nitric oxide in the penis. Nitric oxide then activates the enzyme, guanylate cyclase, which causes the production of cyclic guanosine monophosphate (cGMP). It is the cGMP that is primarily responsible for the erection by affecting the amount of blood that the blood vessels deliver and remove from the penis.