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작성자 Ngan 댓글 0건 조회 11회 작성일 25-05-08 07:35

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The members of the SUV39 household mentioned above are concerned in both euchromatin and heterochromatin, but one other member of the identical household, solicitor article G9a, is the predominant histone H3 K9 methyltransferase in mammalian euchromatin 14 There are two isoforms of G9a within the mouse: the brief form (GenBank accession number NP_671493 ) corresponds to human G9a and the long form ( NP_665829 ), which lacks intron one, has extra Arg-Gly repeats on the amino terminus.

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Common posttranslational modifications embody methylation of the ε-amino group, giving methyl- , dimethyl- , and trimethyllysine The latter occurs in calmodulin Other posttranslational modifications at lysine residues include acetylation , sumoylation , and ubiquitination Collagen contains hydroxylysine , which is derived from lysine by lysyl hydroxylase - Glycosylation of hydroxylysine residues within the endoplasmic reticulum or Golgi apparatus is used to mark sure proteins for secretion from the cell In opsins like rhodopsin and the visual opsins (encoded by the genes OPN1SW , OPN1MW , and OPN1LW ), retinaldehyde types a Schiff base with a conserved lysine residue, and interplay of light with the retinylidene group causes signal transduction in shade vision (See visible cycle for particulars).

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